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Akciğer nodülü ve kitlesi · Patoloji · Yüksek öncelik

Part-solid pulmoner nodül

Part-solid pulmonary nodule

Part-solid pulmoner nodül: yayımlanmış olgu görüntüsü, aksiyel kesit
Görüntü konuyu kısmen gösteriyor; bulgunun bir bölümü seçilebilir.

4 adım

Görüntü: Kim MJ, Hong W, Kim TJ ve ark., “Solitary Pulmonary Capillary Hemangioma: CT and PET-CT Features with Clinicopathologic Correlation.”, 2022, Figure 4. PMC9689303 · doi:10.3390/diagnostics12112618 · CC BY 4.0. Değişiklik: yeniden boyutlandırıldı.

Özet

Part-solid nodülde buzlu cam zemin içinde parankim izlerini örten gerçek solid bileşen bulunur. İnce kesit kontrastsız BT’de toplam lezyon çapı ile solid kısmın ayrı değerlendirilmesi, adenokarsinom spektrumundaki invaziv bileşenle ilişkili değişimi izletir. Solid bileşenin yeni ortaya çıkması veya büyümesi, toplam çap sabit kalırken gözden kaçabilir.

Faz ve pencere

Kontrastsız tanısal
İnce kesit BT’de buzlu cam zemin ile parankimi örten solid odak ayrı değerlendirilir; toplam nodül ve solid bileşen çapları ölçülür.

Önerilen pencereler: Akciğer (G 1500 / M -600), Mediasten (G 350 / M 50).

BT bulguları

  • Damar/bronş izleri buzlu cam kısımda seçilir, solid odakta örtülür.
  • Toplam nodül çapı ile solid bileşenin çapı ayrı kaydedilir.
  • Toplam nodül ve solid bileşen çapları ince kesit BT’de ölçülür; solid bileşenin sınırlarının net belirlenmesi için mediastinal pencere kullanımı önerilir. Mediastinal pencere, lezyon içindeki yağ veya kalsifikasyon varlığını doğrulamaya yardımcı olabilir.
  • Lobülasyon, spikülasyon, plevral çekinti ve hava bronkogramı eşlik edebilir.
  • Seri incelemede yeni solid alan veya solid komponent artışı, toplam çap değişmese de kaydedilir.

Ölçütler ve sınıflamalar

Subsolid nodülde ince kesit ve ölçüm
Kesit kalınlığı <3 mm, ideal olarak 1–1,5 mm; toplam nodül ve solid bileşen ayrı ölçülür.
Fleischner Society 2017 subsolid nodüller
Part-solid nodül, hem buzlu cam hem de solid bileşen içerdiğinden ayrı değerlendirilmelidir; yönetimi hastanın risk faktörlerine ve nodül özelliklerine göre kişiselleştirilir.
ACR Lung-RADS
Tarama nodülü kategorisi toplam boyutun yanı sıra solid bileşenin boyut ve değişimine bağlıdır.
TNM 9. baskı solid-subsolid ölçümü
Klinik T evrelemesinde part-solid primer tümörün boyutu, solid bileşenin en uzun çapına dayanılarak belirlenir; bu yaklaşım güncel TNM evreleme sistemlerinde korunmaktadır.

Normalde

Normal akciğerde damar ve bronş konturları kesintisiz seçilir. Part-solid nodülde damarlar buzlu cam kısmında korunur, solid kısımda silinir; sınırı akciğer ve mediasten pencerelerinde karşılaştır.

Normal BT ile kıyasla

Aynı bölgenin, kaynak veri setinde patoloji içermediği belirtilen bir BT incelemesini kesit kesit kaydırın; organ sınırlarını açarak anatomiyi hasta görüntüsüyle karşılaştırın. Küçük rastlantısal bulgular tümüyle dışlanmamıştır.

Kaynak: TotalSegmentator v2.01 veri seti (Wasserthal ve ark., Radiology: Artificial Intelligence 2023), CC BY 4.0, vaka s1278; organ sınırları veri setinin otomatik segmentasyonundan, birleştirilerek sadeleştirildi. Görüntüler 2,5 mm kesit aralığına yeniden örneklendi.

Ayırıcı tanı

Saf GGN
tüm odakta damar izleri korunur, gerçek solid odak yoktur.
Fokal enfeksiyon
yamalı buzlu cam, sentrilobüler nodüller veya zaman içinde gerileme gösterebilir.
Kısmi atelektazi, özellikle tümöre bağlı kollapsla solid görünüm taklit edebilir.
İnvaziv solid nodül
buzlu cam bileşen olmadan parankimi örter.

Tuzaklar

  • Solid bileşeni toplam nodül çapıyla karıştırmayın; solid bileşen, akciğer penceresindeki damar konturlarıyla örtüşebileceğinden mediastinal pencerede ayrı ölçülür. Mediastinal pencerede solid bileşen, akciğer penceresine göre daha belirgin görünebilir ve daha geniş ölçülebilir.
  • Kalın kesitler küçük nodülleri gizleyebilir; ince kesit görüntüleme (≤1,5 mm) tespit ve karakterizasyon için gereklidir.
  • BT solid komponenti histolojik invaziv komponentle bire bir eşleştirmez.

Kendini dene

  1. Buzlu cam odağın içinde damar kesitlerinin silindiği bölüm var. Lezyon nasıl adlandırılır?

    Cevabı göster

    Part-solid nodül. Buzlu cam ve parankim izlerini örten solid bileşenin birlikteliği part-solid tanımıdır.

  2. Seri BT’de toplam çap benzer, fakat yeni solid odak oluşmuş. Hangi değişiklik kaydedilmeli?

    Cevabı göster

    Solid komponentin yeni oluşumu ve çapı. Solid komponentin ortaya çıkması veya artması, toplam çap sabit olsa da morfolojik değişimdir.

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Kaynaklar

Bu sayfadaki 38 cümle ve 2 quiz sorusu aşağıdaki kaynaklardan alıntılarla tek tek karşılaştırıldı; 10 cümle bu karşılaştırmada düzeltildi (2026-10-08).

  1. CT prediction of malignancy in part-solid pulmonary nodules based on vascular interruption and distortion.pubmed.ncbi.nlm.nih.gov
  2. Evaluating the Patient With a Pulmonary Nodule: A Review.pubmed.ncbi.nlm.nih.gov
  3. Pulmonary Nodules.pubmed.ncbi.nlm.nih.gov
  4. Probability of cancer in pulmonary nodules detected on first screening CT.pubmed.ncbi.nlm.nih.gov
  5. Initial Pulmonary Nodule Management for the Generalist: A Brief Review.pubmed.ncbi.nlm.nih.gov
  6. Low-dose CT screening among never-smokers with or without a family history of lung cancer in Taiwan: a prospective cohort study.pubmed.ncbi.nlm.nih.gov
  7. Accurate diagnosis of pulmonary nodules using a noninvasive DNA methylation test.pubmed.ncbi.nlm.nih.gov
  8. [Not Available].pubmed.ncbi.nlm.nih.gov
  9. Ground-glass nodules of the lung in never-smokers and smokers: clinical and genetic insights.pubmed.ncbi.nlm.nih.gov
  10. Management of Ground-Glass Nodules: When and How to Operate?pubmed.ncbi.nlm.nih.gov
  11. Cancer Risk in Subsolid Nodules in the National Lung Screening Trial.pubmed.ncbi.nlm.nih.gov
  12. Subsolid pulmonary nodules: CT-pathologic correlation using the 2011 IASLC/ATS/ERS classification.pubmed.ncbi.nlm.nih.gov
  13. Performance of ACR Lung-RADS in a Clinical CT Lung Screening Program.pubmed.ncbi.nlm.nih.gov
  14. Genomic characterisation of pulmonary subsolid nodules: mutational landscape and radiological features.pubmed.ncbi.nlm.nih.gov
  15. Ground-glass opacity nodules: histopathology, imaging evaluation, and clinical implications.pubmed.ncbi.nlm.nih.gov
  16. Predictors of Pathologic Tumor Invasion and Prognosis for Ground Glass Opacity Featured Lung Adenocarcinoma.pubmed.ncbi.nlm.nih.gov
  17. Lung Cancers Manifesting as Part-Solid Nodules in the National Lung Screening Trial.pubmed.ncbi.nlm.nih.gov
  18. Tumor Atelectasis Gives Rise to a Solid Appearance in Pulmonary Adenocarcinomas on High-Resolution Computed Tomography.pubmed.ncbi.nlm.nih.gov
  19. How to confront the high prevalence of pulmonary micro nodules (PMNs) in osteosarcoma patients?pubmed.ncbi.nlm.nih.gov
  20. Aggressiveness-guided nodule management for lung cancer screening in Europe-justification for follow-up intervals and definition of growth.pubmed.ncbi.nlm.nih.gov
  21. Prognostic importance of volumetric measurements in stage I lung adenocarcinoma.pubmed.ncbi.nlm.nih.gov
  22. Accuracy of solid portion size measured on multiplanar volume rendering images for assessing invasiveness in lung adenocarcinoma manifesting as subsolid nodules.pubmed.ncbi.nlm.nih.gov
  23. Evaluation of the solitary pulmonary nodule: size matters, but do not ignore the power of morphology.pubmed.ncbi.nlm.nih.gov
  24. Differential diagnosis of solitary pulmonary nodules with dual-source spiral computed tomography.pubmed.ncbi.nlm.nih.gov
  25. CT-based Radiologic Ternary Classification Model in Predicting Pathologic Invasiveness of Pulmonary Nonsolid Nodules.pubmed.ncbi.nlm.nih.gov
  26. Clinical and Radiological Characteristics to Differentiate Between EGFR Exon 21 and Exon 19 Mutations in Patients With Lung Adenocarcinoma: A Systematic Literature Review and Meta-Analysis.pubmed.ncbi.nlm.nih.gov
  27. CT characteristics of solitary pulmonary capillary hemangioma versus lung adenocarcinoma.pubmed.ncbi.nlm.nih.gov
  28. Pulmonary fissure segmentation on CT.pubmed.ncbi.nlm.nih.gov
  29. Robust anisotropic Gaussian fitting for volumetric characterization of pulmonary nodules in multislice CT.pubmed.ncbi.nlm.nih.gov
  30. Normative values for lung, bronchial sizes, and bronchus-artery ratios in chest CT scans: from infancy into young adulthood.pubmed.ncbi.nlm.nih.gov
  31. A left lung abscess with a displaced subsegmental bronchus and anomalous pulmonary artery and vein: a case report.pubmed.ncbi.nlm.nih.gov
  32. Computed tomographic characterization of the pulmonary system in clinically normal alpacas.pubmed.ncbi.nlm.nih.gov
  33. Guidelines for Management of Incidental Pulmonary Nodules Detected on CT Images: From the Fleischner Society 2017.pubmed.ncbi.nlm.nih.gov
  34. Updated Fleischner Society Guidelines for Managing Incidental Pulmonary Nodules: Common Questions and Challenging Scenarios.pubmed.ncbi.nlm.nih.gov
  35. Nodule characterization: subsolid nodules.pubmed.ncbi.nlm.nih.gov
  36. Cost-Effectiveness of Treatment Thresholds for Subsolid Pulmonary Nodules in CT Lung Cancer Screening.pubmed.ncbi.nlm.nih.gov
  37. Improved interobserver agreement on nodule type and Lung-RADS classification of subsolid nodules using computer-aided solid component measurement.pubmed.ncbi.nlm.nih.gov
  38. A problem with clinical T factor in the 8th TNM edition: Prognosis and EGFR mutation status of small sized lung cancers with difficulty to measure the diameter of solid component in part-solid tumor.pubmed.ncbi.nlm.nih.gov
  39. Prognostic impact of a ground-glass opacity component in clinical stage IA non-small cell lung cancer.pubmed.ncbi.nlm.nih.gov
  40. Evaluation of solid portions in non-small cell lung cancer-the solid part is not always measurable for clinical T factor.pubmed.ncbi.nlm.nih.gov
  41. Invasive pulmonary adenocarcinomas versus preinvasive lesions appearing as ground-glass nodules: differentiation by using CT features.pubmed.ncbi.nlm.nih.gov
  42. High versus low attenuation thresholds to determine the solid component of ground-glass opacity nodules.pubmed.ncbi.nlm.nih.gov
  43. Various computed tomography findings of 2009 H1N1 influenza in 17 patients with relatively mild illness.pubmed.ncbi.nlm.nih.gov
  44. Thoracic CT findings of novel influenza A (H1N1) infection in immunocompromised patients.pubmed.ncbi.nlm.nih.gov
  45. Noninfectious Generalized Bronchiolitis in the Setting of Allogeneic Stem Cell Transplantation: A Potential Mimic of Lower Respiratory Tract Infection.pubmed.ncbi.nlm.nih.gov
  46. Comparison of 10-year Survival Outcomes between CT Surveillance and Surgery for Ground-Glass Nodules.pubmed.ncbi.nlm.nih.gov
  47. Software-based risk stratification of pulmonary adenocarcinomas manifesting as pure ground glass nodules on computed tomography.pubmed.ncbi.nlm.nih.gov
  48. Lung cancers associated with cystic airspaces: CT features and pathologic correlation.pubmed.ncbi.nlm.nih.gov
  49. Clinicopathological Features and Prognosis of Lung Adenocarcinoma Presenting as Ground-Glass Opacity: A Single-Center Experience.pubmed.ncbi.nlm.nih.gov
  50. Dual-Energy Computed Tomography Lung in patients of Pulmonary Tuberculosis.pubmed.ncbi.nlm.nih.gov
  51. Efficacy of measuring the invasive diameter of lung adenocarcinoma using mediastinal window settings: A retrospective study.pubmed.ncbi.nlm.nih.gov
  52. Thoracic Sarcoidosis: Imaging with High Resolution Computed Tomography.pubmed.ncbi.nlm.nih.gov
  53. Correlation exploration among CT imaging, pathology and genotype of pulmonary ground-glass opacity.pubmed.ncbi.nlm.nih.gov
  54. [Clinicopathological characteristics and imaging features of pulmonary adenocarcinoma with micropapillary pattern].pubmed.ncbi.nlm.nih.gov
  55. Differential Diagnosis of Nonabsorbable Inflammatory and Malignant Subsolid Nodules with a Solid Component ≤5 mm.pubmed.ncbi.nlm.nih.gov
  56. [Results of low-dose computed tomography (LDCT) screening for early lung cancer: prevalence in 4 690 asymptomatic participants].pubmed.ncbi.nlm.nih.gov
  57. CT- and computer-based features of small hamartomas.pubmed.ncbi.nlm.nih.gov
  58. Interobserver size measurement variability in part-solid lung adenocarcinoma using pre-operative computed tomography.pubmed.ncbi.nlm.nih.gov
  59. Controversies on lung cancers manifesting as part-solid nodules.pubmed.ncbi.nlm.nih.gov
  60. Clinical Outcomes of Resected Pure Ground-Glass, Heterogeneous Ground-Glass, and Part-Solid Pulmonary Nodules.pubmed.ncbi.nlm.nih.gov
  61. A decrease in the size of ground glass nodules may indicate the optimal timing for curative surgery.pubmed.ncbi.nlm.nih.gov
  62. Differentiation between malignancy and inflammation in pulmonary ground-glass nodules: The feasibility of integrated (18)F-FDG PET/CT.pubmed.ncbi.nlm.nih.gov
  63. Predictors of Diagnostic Yield in Shape-Sensing Robotic-Assisted Bronchoscopy (ssRAB): A Retrospective Single-Center Study.pubmed.ncbi.nlm.nih.gov
  64. [Three-dimensional Mass Measurement of Subsolid Pulmonary Nodules on Chest CT: Intra and Inter-observer Variability].pubmed.ncbi.nlm.nih.gov
  65. Subsolid Lung Adenocarcinomas: Radiological, Clinical and Pathological Features and Outcomes.pubmed.ncbi.nlm.nih.gov
  66. Clinical Versus Pathological Staging in Patients with Resected Ground Glass Pulmonary Lesions.pubmed.ncbi.nlm.nih.gov
  67. Lung nodules: size still matters.pubmed.ncbi.nlm.nih.gov
  68. Rate of benign nodule resection in a lung cancer screening program.pubmed.ncbi.nlm.nih.gov
  69. ACR Appropriateness Criteria® Indolent Lung Cancer.pubmed.ncbi.nlm.nih.gov
  70. Improving the preoperative diagnosis of invasive lung adenocarcinoma by combining multiplanar volume rendering (MPVR)-based solid component measurement with pathological analysis.pubmed.ncbi.nlm.nih.gov
  71. Decoding Malignant Lung Ground Glass Opacities: A Radiologic-Pathologic Study From Pure to Semi-Solid Lesions.pubmed.ncbi.nlm.nih.gov
  72. Predicting STAS in peripheral stage I lung adenocarcinoma: the incremental value of CT-based tumor disappearance rate, with a focus on part-solid nodules.pubmed.ncbi.nlm.nih.gov
  73. Natural history and clinical characteristics of pulmonary subsolid nodules in pediatric patients: a cohort study.pubmed.ncbi.nlm.nih.gov
  74. Short-term quantitative CT changes in synchronous ground-glass nodules during immune checkpoint inhibitor therapy in patients with lung cancer.pubmed.ncbi.nlm.nih.gov
  75. Congenital pulmonary airway malformation mimicking lung cancer in adults: a pitfall in oncologic diagnosis.pubmed.ncbi.nlm.nih.gov
  76. Incidental Lung Lesions on the CT Component of Oncologic FDG PET/CT: A Pictorial Review of Interpretive Pitfalls and Diagnostic Clues.pubmed.ncbi.nlm.nih.gov
  77. International association for the study of lung cancer/american thoracic society/european respiratory society international multidisciplinary classification of lung adenocarcinoma.pubmed.ncbi.nlm.nih.gov
  78. Long-term safety and effectiveness of the "OptEase" vena cava filter.pubmed.ncbi.nlm.nih.gov
  79. AI-accelerated 3D gradient echo versus ultrashort echo time MRI for lung nodule detection and measurement.pubmed.ncbi.nlm.nih.gov
  80. Chest CT-detected pulmonary nodules across the COVID-19 pandemic in Guangzhou, China: a regression discontinuity-in-time study, 2013-2023.pubmed.ncbi.nlm.nih.gov
  81. Case-matched retrieval improves textual alignment of LLM-generated radiology impressions.pubmed.ncbi.nlm.nih.gov
  82. Incidental pulmonary findings on CT in daily practice: the nodule and the interstitial lung abnormalities - what's old, what's new.pubmed.ncbi.nlm.nih.gov
  83. The probability of lung cancer in patients with pulmonary nodules detected via low-dose computed tomography screening in China.pubmed.ncbi.nlm.nih.gov
  84. Evaluation of benign and malignant pulmonary nodules based on clinical and contrast-enhanced computed tomography data: a multicenter study.pubmed.ncbi.nlm.nih.gov
  85. Suprasellar Desmoplastic Infantile Ganglioglioma in a 7-Month-Old Infant: A Rare Diagnostic Consideration in Infant Suprasellar Masses.pubmed.ncbi.nlm.nih.gov
  86. Risk of Malignancy in Cystic Lung Lesions in a Lung Cancer CT Screening Program.pubmed.ncbi.nlm.nih.gov
  87. Artificial intelligence-based automated matching of pulmonary nodules on follow-up chest CT.pubmed.ncbi.nlm.nih.gov
  88. Robotic-assisted bronchoscopy in dye localization in thoracoscopic pulmonary nodule resection: An initial experience.pubmed.ncbi.nlm.nih.gov
  89. Recent trends in scientific research in chest radiology: What to do or not to do? That is the critical question in research.pubmed.ncbi.nlm.nih.gov
  90. Screening for lung cancer using thin-slice low-dose computed tomography in southwestern China: a population-based real-world study.pubmed.ncbi.nlm.nih.gov
  91. Clinically Relevant Motion of Canine Thoracic Tumors Is Seen Between Inspiratory and Expiratory Breath Holds on Computed Tomography Performed for Radiation Treatment Planning.pubmed.ncbi.nlm.nih.gov
  92. Development of a Two Stage Pipeline for Robust Pulmonary Nodule Detection in Consecutive CT Slices.pubmed.ncbi.nlm.nih.gov
  93. Clinical correlates and short-term prognostic value of CT-detected subclinical pulmonary congestion in acute STEMI without overt heart failure.pubmed.ncbi.nlm.nih.gov
  94. Artificial intelligence-based density proportion analysis in predicting the invasiveness of neoplastic ground-glass nodules.pubmed.ncbi.nlm.nih.gov
  95. Clinical TNM Lung Cancer Staging: A Diagnostic Algorithm with a Pictorial Review.pubmed.ncbi.nlm.nih.gov
  96. AI driven hybrid convolutional and transformer based deep learning architecture for precise lung nodule classification.pubmed.ncbi.nlm.nih.gov
  97. A narrative review on CT-based evaluation and prediction of lung nodule growth: current status and future directions.pubmed.ncbi.nlm.nih.gov
  98. Deep learning-based super-resolution ultrashort echo time MRI for pulmonary nodule detection and longitudinal assessment in emphysema.pubmed.ncbi.nlm.nih.gov
  99. The Stockholm Pilot study for Lung cancer Screening (Stockholm PLUS): feasibility of baseline low-dose CT lung cancer screening in a high-risk Swedish female population.pubmed.ncbi.nlm.nih.gov
  100. Imaging features of lung cancer with cystic airspaces: clinical utility, challenges, and perspectives.pubmed.ncbi.nlm.nih.gov
  101. Is surgical lymph node assessment justified for ground glass opacity-dominant lung adenocarcinoma?pubmed.ncbi.nlm.nih.gov
  102. HPV-associated Oropharyngeal Squamous Cell Carcinoma: An Imaging Framework for AJCC Version 9 TNM Staging.pubmed.ncbi.nlm.nih.gov
  103. Impact of Consolidation-to-Tumor Ratio on Prognosis After Radiation therapy for Lung Cancer With a Lesion Diameter of 3 cm or Less.pubmed.ncbi.nlm.nih.gov
  104. Nivolumab Plus Lenvatinib and Intra-Arterial Locoregional Therapy as First-Line Treatment for Unresectable Hepatocellular Carcinoma: A Real-World Study.pubmed.ncbi.nlm.nih.gov
  105. Diagnostic significance of cancer antigen 125/carcinoembryonic antigen ratio combined with IOTA-ADNEX model in discriminating between primary ovarian cancer and ovarian metastases.pubmed.ncbi.nlm.nih.gov
  106. CT-Guided Transthoracic Core-Needle Biopsy of Pulmonary Nodules: Current Practices, Efficacy, and Safety Considerations.pubmed.ncbi.nlm.nih.gov
  107. Unveiling the synergetic benefits of the tunneling technique using stapler tractor in precise resection of lung segments: a retrospective cohort study.pubmed.ncbi.nlm.nih.gov
  108. Lipoid Pneumonia: HRCT and MRI Spectrum, Diagnostic Pitfalls, and Imaging-Based Diagnostic Workflow.pubmed.ncbi.nlm.nih.gov
  109. Pulmonary histoplasmosis mimicking recurrent lung adenocarcinoma: A case report.pubmed.ncbi.nlm.nih.gov
  110. Chest tuberculosis: Radiological review and imaging recommendations.pubmed.ncbi.nlm.nih.gov

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