Klinik Atölye

Çocuk: göğüs ve nöro · Patoloji · Yüksek öncelik

Pediatrik beyin tümörleri: BT’de kitle ve kalsifikasyon

Pediatric brain tumors: CT mass and calcification

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Pediatrik beyin tümörleri: BT’de kitle ve kalsifikasyon: yayımlanmış olgu görüntüsü, aksiyel kesit
Görüntü konuyu kısmen gösteriyor; bulgunun bir bölümü seçilebilir.

4 adım

Görüntü: see above, “Craniopharyngioma”, Wikimedia Commons · CC BY 2.0. Değişiklik: yeniden boyutlandırıldı.

Özet

Çocukta yeni nörolojik bulgu, nöbet veya kafa içi basınç artışı belirtileri beyin kitlesinin ilk kez BT’de fark edilmesine yol açabilir. Kontrastsız BT kanama, kalsifikasyon, ödem, hidrosefali ve kitle etkisini hızlıca ortaya koyar; BT tümör tipini güvenilir biçimde belirlemez. Kontrastlanan solid ve kistik bileşenleri gösterebilir, ancak karakterizasyon ve yayılım için MR daha duyarlıdır. Kitle etkisi veya BOS yolu tıkanması atlanırsa acil kötüleşme riski gözden kaçar.

Faz ve pencere

Kontrastsız tanısal
Kitle atenüasyonu, kalsifikasyon, akut kanama, çevresel ödem, orta hat kayması ve ventriküler obstrüksiyon değerlendirilir; kontrastsız seri akut BT değerlendirmesinin temelidir.
Kontrastlı
Kontrastlı BT’de kavernöz malformasyonlarda kontrastlanma minimal olabilir veya görülmeyebilir; bu BT bulguları özgül değildir. BT bulguları tümör alt tipini tek başına belirlemez; kesin tanıda histopatolojik inceleme gerekir.

Önerilen pencereler: Beyin (G 80 / M 40), Kemik (G 1800 / M 400).

BT bulguları

  • Parankim içinde fokal kitle ile çevresindeki ödem ve kitle etkisi değerlendirilir.
  • Lezyonun gri cevhere göre hiperdens, izodens ya da hipodens olması tek başına histolojik tanı koydurmaz.
  • Kalsifikasyonun tümör içinde noktasal, kaba veya kümeli dağılımı kaydedilir.
  • İntralezyonel kanama ve nekrotik/kistik düşük atenüasyon alanları ayrı bileşenler olarak tanımlanır.
  • Parankimal kitlenin çevresinde vazojenik ödem ve komşu ventriküllerde bası veya obstrüksiyon izlenerek kitle etkisi değerlendirilir.
  • Kontrastlı BT elde edilmişse solid doku, duvar veya nodül kontrastlanabilir; bu görünüm tümör alt tipini tek başına belirlemez ve MRI ile karakterizasyonun yerini tutmaz.
  • Ventriküler sistem veya bazal sistern basısı hidrosefali ve herniasyon riski açısından gözden geçirilir.

Normalde

Ventrikül genişlemesi, BOS akımındaki tıkanıklıkla ilişkili olabileceği gibi beyin atrofisine de eşlik edebilir. Kaba lezyon içi kalsifikasyon, erişkin tip diffüz gliomlarda oligodendrogliomayı destekleyen görüntüleme özelliklerindendir.

Normal BT ile kıyasla

Aynı bölgenin, kaynak veri setinde patoloji içermediği belirtilen bir BT incelemesini kesit kesit kaydırın; organ sınırlarını açarak anatomiyi hasta görüntüsüyle karşılaştırın. Küçük rastlantısal bulgular tümüyle dışlanmamıştır.

Kaynak: TotalSegmentator v2.01 veri seti (Wasserthal ve ark., Radiology: Artificial Intelligence 2023), CC BY 4.0, vaka s0103; organ sınırları veri setinin otomatik segmentasyonundan, birleştirilerek sadeleştirildi. Görüntüler 2,5 mm kesit aralığına yeniden örneklendi.

Ayırıcı tanı

İntraparenkimal kanama BT’de hiperdens bir bileşen olarak görülebilir.
Beyin apsesi, kontrastlı MR’da halka kontrastlanması ve santral difüzyon kısıtlanması gösterebilir.
Enfarkt BT’de saptanabilir.
İntrakraniyal kalsifikasyonlara eşlik eden kistik lezyonlar primer beyin tümörünü taklit edebilir.

Tuzaklar

  • Arka fossa tümörleri sınırlı boşluk nedeniyle hızlı hidrosefali ve beyinsapı basısına yol açabilir; ventriküler sistem ve sisternlerin obstrüksiyonu acil olarak değerlendirilmelidir.
  • Kavernöz malformasyonların BT bulguları özgül olmayabilir ve tümörleri taklit edebilir.
  • BT bulguları tek başına tümörün histopatolojik tanısını belirlemez.

Kendini dene

  1. Çocukta kontrastsız BT’de heterojen kitle, kalsifikasyon ve çevresel ödem var. BT’den hangi sonuç çıkar?

    Cevabı göster

    Kitle ve kitle etkisi. BT, kitleyi, iç yoğunlukları ve bası etkisini gösterir; tümörün histolojik veya moleküler alt grubunu belirlemez.

  2. Foramen Monro tıkanıklığından şüphe edilen bir bebekte iki lateral ventrikül geniş, üçüncü ve dördüncü ventriküller normal boyuttadır. Bu patern en iyi nasıl açıklanır?

    Cevabı göster

    Foramen Monro tıkanıklığına bağlı obstrüktif hidrosefali. Foramen Monro tıkanıklığı obstrüktif hidrosefaliye yol açabilir; bildirilen olguda lateral ventriküller geniş, üçüncü ve dördüncü ventriküller normal boyuttadır.

İlgili konular

Kaynaklar

Bu sayfadaki 34 cümle ve 2 quiz sorusu aşağıdaki kaynaklardan alıntılarla otomatik olarak karşılaştırıldı; 16 cümle bu karşılaştırmada düzeltildi (2026-10-09).

  1. Diagnostic challenges of a giant cerebral cavernous malformation mimicking a glioma in a 16-year-old malepmc.ncbi.nlm.nih.gov
  2. Preliminary investigation of the clinical value of thoracic ultrasound in pediatric pleuropulmonary blastoma: a comparative analysis with computed tomography and pathologypmc.ncbi.nlm.nih.gov
  3. Imaging diagnosis of adult-type diffuse gliomas in the era of WHO CNS5 and cIMPACT-NOW updates 8–11: a narrative reviewpmc.ncbi.nlm.nih.gov
  4. An intra-axial wolf in extra-axial clothing: A rare case of high-grade astrocytoma and literature reviewpmc.ncbi.nlm.nih.gov
  5. Case Report: Giant acute hemorrhagic colloid cyst in the septum pellucidum-foramen of Monro region with obstructive hydrocephalus in an 8-month-old infantpmc.ncbi.nlm.nih.gov
  6. Retinoblastoma in an adult.pubmed.ncbi.nlm.nih.gov
  7. Post-traumatic seizure with an unexpected finding.pubmed.ncbi.nlm.nih.gov
  8. A cortical dysembryoplastic neuroepithelial tumor initially occurring in the periventricular white matter.pubmed.ncbi.nlm.nih.gov
  9. Correlation of CT signs with lymphatic metastasis and pathology of neuroblastoma in children.pubmed.ncbi.nlm.nih.gov
  10. Child dermoid cyst mimicking a craniopharyngioma: the benefit of MRI T2-weighted diffusion sequence.pubmed.ncbi.nlm.nih.gov
  11. Alpha-fetoprotein secretion in a craniopharyngioma. Are craniopharyngiomas part of the germ cell tumor family?pubmed.ncbi.nlm.nih.gov
  12. Surgical management of a giant glial hamartoma in a pediatric patient: a case report.pubmed.ncbi.nlm.nih.gov
  13. An atypical location of pineoblastoma RB1 subgroup without pineal or retinal tumor.pubmed.ncbi.nlm.nih.gov
  14. Multimodal Cytogenetic and Molecular Approach for the Detection of a Constitutional Balanced Paracentric Inversion Disrupting RB1 in an Infant With Bilateral Retinoblastoma.pubmed.ncbi.nlm.nih.gov
  15. Diffuse leptomeningeal glioneuronal tumor mimicking chronic inflammatory and tuberculous meningitis.pubmed.ncbi.nlm.nih.gov
  16. Fatal malignant cerebral vasospasm following pediatric craniopharyngioma resection: A case report and literature review.pubmed.ncbi.nlm.nih.gov
  17. Clinical and Radiological Features of a Large Intracranial Hydatid Cyst: A New Case Report.pubmed.ncbi.nlm.nih.gov
  18. Case Report: A case series of Lhermitte-Duclos disease with surgical intervention.pubmed.ncbi.nlm.nih.gov
  19. Guidelines for the Diagnosis and Clinical Management of Cavernous Malformations of the Brain and Spinal Cord: Consensus Recommendations Based on a Systematic Literature Review by the Alliance to Cure Cavernous Malformation Clinical Advisory Board Experts Panel.pubmed.ncbi.nlm.nih.gov
  20. Clival and Paraclival Lesions: A Pictorial Review.pubmed.ncbi.nlm.nih.gov
  21. Spectral CT and Photon-counting Detector CT: Principles and Applications in Neuroradiology.pubmed.ncbi.nlm.nih.gov
  22. Case Report: Androgen-secreting pediatric adrenocortical tumor of uncertain malignant potential presenting with virilization in a 19-month-old girl.pubmed.ncbi.nlm.nih.gov
  23. Ultra-high-field 7-Tesla MRI in neuro-oncology: a narrative review of current applications and future directions.pubmed.ncbi.nlm.nih.gov
  24. Acute fulminant cerebellitis in children: a case series and literature review on diagnostic challenges and management strategies.pubmed.ncbi.nlm.nih.gov
  25. Late peritoneal metastases of medulloblastoma following ventriculoperitoneal shunting: A case report.pubmed.ncbi.nlm.nih.gov
  26. Anatomical Approaches for Insertion Sites of External Ventricular Drainage Catheters.pubmed.ncbi.nlm.nih.gov
  27. Intracranial Mesenchymal Tumor with FET-CREB Gene Fusion: A Case Report of Late Recurrence.pubmed.ncbi.nlm.nih.gov
  28. Case Report: Giant acute hemorrhagic colloid cyst in the septum pellucidum-foramen of Monro region with obstructive hydrocephalus in an 8-month-old infant.pubmed.ncbi.nlm.nih.gov
  29. Imaging diagnosis of cystic intraparenchymal brain neoplasms.pubmed.ncbi.nlm.nih.gov
  30. Whole-Body MRI Versus <sup>18</sup>F-FDG-PET/CT for the Detection of Nodal and Distant Metastases in Pediatric Patients with Solid Tumors.pubmed.ncbi.nlm.nih.gov
  31. Clinical Applications of Hyperpolarized Magnetic Resonance Imaging in Brain Tumors: Current Evidence and Future Opportunities.pubmed.ncbi.nlm.nih.gov
  32. Laser insterstitial thermal therapy followed by craniotomy for tumor resection for pediatric diffuse midline glioma: illustrative case.pubmed.ncbi.nlm.nih.gov
  33. Imaging for Pediatric Head and Neck Emergencies: Critical Insights.pubmed.ncbi.nlm.nih.gov
  34. Preliminary investigation of the clinical value of thoracic ultrasound in pediatric pleuropulmonary blastoma: a comparative analysis with computed tomography and pathology.pubmed.ncbi.nlm.nih.gov
  35. Imaging of Skull Base Tumors.pubmed.ncbi.nlm.nih.gov
  36. Neoplasms and tumor-like lesions of the sellar region: imaging findings with correlation to pathology and 2021 WHO classification.pubmed.ncbi.nlm.nih.gov
  37. Radiohistogenomics of pediatric low-grade neuroepithelial tumors.pubmed.ncbi.nlm.nih.gov
  38. Commentary: an eye on PET quantification.pubmed.ncbi.nlm.nih.gov
  39. Cancer predisposition syndromes: an imaging review.pubmed.ncbi.nlm.nih.gov
  40. CUX1::MET fusion defines an indolent subtype of diffuse low-grade glioma, MAPK pathway-altered.pubmed.ncbi.nlm.nih.gov
  41. Olfactory Groove Meningioma Mimicking Late-Life Depression: A Case Report.pubmed.ncbi.nlm.nih.gov
  42. Human biomarker navigator.pubmed.ncbi.nlm.nih.gov
  43. Special Issue: EACR 2026 Congress: Innovative Cancer Science, 8-11 June 2026.pubmed.ncbi.nlm.nih.gov
  44. A Thorough Review of the Clinical Applications of Artificial Intelligence in Lung Cancer.pubmed.ncbi.nlm.nih.gov
  45. Role of mixed reality in the workflow of complex neurooncological surgeries: a case analysis in thalamic surgery.pubmed.ncbi.nlm.nih.gov
  46. Cerebrospinal fluid diversion prior to posterior fossa tumor resection in adults: A systematic review.pubmed.ncbi.nlm.nih.gov
  47. Primary intracranial rhabdomyosarcoma: A systematic review of existing literature from 2000 to 2024.pubmed.ncbi.nlm.nih.gov
  48. Imaging Evaluation of Acute Traumatic Brain Injury.pubmed.ncbi.nlm.nih.gov
  49. Secondary Brain Injury After Parenchymal Cerebral Hemorrhage in Humans: The Role of NOX2-Mediated Oxidative Stress and Endothelin-1.pubmed.ncbi.nlm.nih.gov
  50. Cerebral microbleeds: Causes, clinical relevance, and imaging approach - A narrative review.pubmed.ncbi.nlm.nih.gov
  51. Spectrum of neurological complications following COVID-19 vaccination.pubmed.ncbi.nlm.nih.gov
  52. Breast cystic echinococcosis with ultrasonographic "cerebral gyrus sign": a case report.pubmed.ncbi.nlm.nih.gov
  53. Management of pneumonia by the emergency radiologist.pubmed.ncbi.nlm.nih.gov
  54. Fulminant cerebral edema in the setting of acute dengue fever after mechanical thrombectomy in a patient with massive stroke and severe hypoalbuminemia: a case report.pubmed.ncbi.nlm.nih.gov
  55. Structure-aware medical image fusion via mean curvature enhancement in the contourlet domain.pubmed.ncbi.nlm.nih.gov
  56. A fulminant presentation of post-COVID-19 necrotizing pneumonia and ischemic stroke in an 8-year-old girl: A case report and literature review.pubmed.ncbi.nlm.nih.gov
  57. Cerebroretinal Microangiopathy with Calcifications and Cysts (CRMCC): A 5-Year Diagnostic Challenge.pubmed.ncbi.nlm.nih.gov
  58. A Rare Case of Neonatal Kaposiform Hemangioendothelioma With Kasabach-Merritt Phenomenon Presenting as an Abdominal Mass Without Cutaneous Manifestations.pubmed.ncbi.nlm.nih.gov
  59. Beyond the leptomeningeal angioma: a comprehensive review of MR imaging features of Sturge-Weber Syndrome, from early vascular responses to tissue necrosis.pubmed.ncbi.nlm.nih.gov
  60. Multimodal imaging in neuro-ophthalmology.pubmed.ncbi.nlm.nih.gov
  61. Microvascular Ultrasound Imaging in the Neonatal Brain: From Advanced Doppler to Super-Resolution.pubmed.ncbi.nlm.nih.gov
  62. Three-Dimensional Constructive Interference in Steady State (3D CISS) Imaging and Clinical Applications in Brain Pathology.pubmed.ncbi.nlm.nih.gov
  63. Cerebral hydatidosis in children from an endemic region: Epidemiology, diagnosis, and management.pubmed.ncbi.nlm.nih.gov
  64. Imaging of ependymomas: MRI and CT.pubmed.ncbi.nlm.nih.gov
  65. Neuroimaging in traumatic brain imaging.pubmed.ncbi.nlm.nih.gov
  66. Obstacles and Trials in Treating Primary Brain Tumors.pubmed.ncbi.nlm.nih.gov
  67. Artificial intelligence in brain tumor diagnosis and surgical planning: Recent advances.pubmed.ncbi.nlm.nih.gov
  68. Enhancing decision-making in surgery for a large temporocorneal meningioma through an explainable human-AI collaboration: a case report.pubmed.ncbi.nlm.nih.gov
  69. Left Pulvinar Thalamic Tumor with Ventricular Atrial Extension Presenting as Network-Level Cognitive and Gait Dysfunction.pubmed.ncbi.nlm.nih.gov
  70. Medical hyperspectral imaging: an updated review of technology advancements and biomedical applications.pubmed.ncbi.nlm.nih.gov
  71. EACR 2025 Congress: Innovative Cancer Science, 16-19 June 2025.pubmed.ncbi.nlm.nih.gov
  72. Clinical and imaging manifestations of metastases from rare sites.pubmed.ncbi.nlm.nih.gov
  73. Society for Cardiovascular Magnetic Resonance 2024 Cases of SCMR case series.pubmed.ncbi.nlm.nih.gov
  74. Cerebral Abscess Masquerading as Tuberculoma in a Post-Renal Transplant Chronic Kidney Disease Patient: A Diagnostic and Therapeutic Challenge.pubmed.ncbi.nlm.nih.gov
  75. Amyloid-related imaging abnormalities (ARIA) in anti-amyloid therapies for Alzheimer's disease: An update from the Alzheimer's Association ARIA workgroup.pubmed.ncbi.nlm.nih.gov
  76. Anatomy-Guided Microsurgical Resection of a Dominant Frontal Lobe Tumor Without Intraoperative Adjuncts: A Case Report from a Resource-Limited Context.pubmed.ncbi.nlm.nih.gov
  77. Anatomically Precise Microsurgical Resection of a Posterior Fossa Cerebellar Metastasis in an Elderly Patient with Preservation of Venous Outflow, Dentate Nucleus, and Cerebrospinal Fluid Pathways.pubmed.ncbi.nlm.nih.gov
  78. Regulation of brain fluid volumes and pressures: basic principles, intracranial hypertension, ventriculomegaly and hydrocephalus.pubmed.ncbi.nlm.nih.gov
  79. Illuminating radiogenomic signatures in pediatric-type diffuse gliomas: insights into molecular, clinical, and imaging correlations. Part I: high-grade group.pubmed.ncbi.nlm.nih.gov
  80. First reported case in Brazil of intraventricular pilocytic astrocytoma in an adult patient with literature review.pubmed.ncbi.nlm.nih.gov
  81. Retinal and Choroidal Vascular Changes Associated with Vitamin D Deficiency.pubmed.ncbi.nlm.nih.gov
  82. Technical considerations of neuroendoscopic management of obstructive hydrocephalus secondary to intraventricular hemorrhage.pubmed.ncbi.nlm.nih.gov
  83. Foramen of Monro choroid plexus papilloma: An extremely rare location managed by endoscopic resection.pubmed.ncbi.nlm.nih.gov
  84. Case Report: Occlusion of the foramen of Monro treated with endoscopic septostomy and foraminotomy in a preterm neonate.pubmed.ncbi.nlm.nih.gov
  85. Ependymal Tumors: Overview of the Recent World Health Organization Histopathologic and Genetic Updates with an Imaging Characteristic.pubmed.ncbi.nlm.nih.gov
  86. Diagnosis of choroid plexus papilloma: Current perspectives and future directions.pubmed.ncbi.nlm.nih.gov
  87. SMARCB1-deficient sinonasal carcinoma in a pediatric patient: Imaging findings and differential diagnosis of a rare entity.pubmed.ncbi.nlm.nih.gov
  88. Lung adenocarcinoma dural metastasis at the petroclival region mimicking meningioma: a frozen-section diagnostic pitfall. Illustrative case.pubmed.ncbi.nlm.nih.gov
  89. Primary cerebellar angiosarcoma: A rare case of posterior fossa vascular tumor with hemorrhagic presentation and favorable surgical outcome.pubmed.ncbi.nlm.nih.gov
  90. Physiological biodistribution of <sup>18</sup>F-fluciclovine PET in the head: as a baseline for interpretation in patients with suspected glioma.pubmed.ncbi.nlm.nih.gov
  91. Acute Massive Spontaneous Intratumoral Hemorrhage in a Pediatric Atypical Teratoid/Rhabdoid Tumor: A Case Report.pubmed.ncbi.nlm.nih.gov
  92. Obstructive hydrocephalus due to choroid plexus carcinoma of third ventricle in pediatric: A rare case report.pubmed.ncbi.nlm.nih.gov
  93. Dual-Energy CT: What the Neuroradiologist Should Know.pubmed.ncbi.nlm.nih.gov
  94. Cerebellum and neurodegenerative diseases: Beyond conventional magnetic resonance imaging.pubmed.ncbi.nlm.nih.gov
  95. Multidisciplinary Management of Pediatric Craniopharyngioma: From Diagnosis to Long-Term Outcomes.pubmed.ncbi.nlm.nih.gov
  96. Understanding Photon-Counting CT: Physics, Detector Technology, and Image Reconstructions.pubmed.ncbi.nlm.nih.gov
  97. Imaging of brain tumors in children: the basics-a narrative review.pubmed.ncbi.nlm.nih.gov
  98. Pineal Calcification, Melatonin Production, Aging, Associated Health Consequences and Rejuvenation of the Pineal Gland.pubmed.ncbi.nlm.nih.gov
  99. The morphological and functional characteristics of the pineal gland.pubmed.ncbi.nlm.nih.gov
  100. Pediatric Stroke Imaging.pubmed.ncbi.nlm.nih.gov
  101. Patterns of injury and violence in Yaoundé Cameroon: an analysis of hospital data.pubmed.ncbi.nlm.nih.gov
  102. Practical guidelines on imaging of retinoblastoma: a 2025 update on behalf of the European Retinoblastoma Imaging Collaboration and the European Retinoblastoma Group.pubmed.ncbi.nlm.nih.gov
  103. The pathogenesis of cerebral small vessel disease and vascular cognitive impairment.pubmed.ncbi.nlm.nih.gov
  104. Molecular profiling of pediatric medulloblastoma in Kazakhstan: Genomic alterations, subgroup distribution, and survival.pubmed.ncbi.nlm.nih.gov
  105. Diagnostic imaging and emerging image-guided neurointervention in brain tumors: a narrative review.pubmed.ncbi.nlm.nih.gov
  106. Posterior fossa ependymoma: a comprehensive review of molecular classification, management guidelines, and clinical outcomes (Part I of ependymomas across compartments).pubmed.ncbi.nlm.nih.gov
  107. A rare case of primary cardiac sarcoma with both intracranial metastasis and embolic infarction in a pediatric patient.pubmed.ncbi.nlm.nih.gov
  108. Acute Truncal Ataxia After a Minor Head Trauma Revealing a Pediatric Cerebellar Pilocytic Astrocytoma.pubmed.ncbi.nlm.nih.gov
  109. Severe Diabetic Ketoacidosis With Fatal Cerebral Edema in an Adult.pubmed.ncbi.nlm.nih.gov
  110. Individualized treatment for pediatric intracranial aneurysms in China: case series and literature review.pubmed.ncbi.nlm.nih.gov
  111. AI-Based Approaches for the Identification and Quantification of Traumatic Brain Injury in Computed Tomography Imaging: Systematic Review.pubmed.ncbi.nlm.nih.gov
  112. Comparative study on imaging characteristics of pilocytic astrocytomas in children and adolescents.pubmed.ncbi.nlm.nih.gov
  113. Radiological diagnosis of calcified intra- and extra-ventricular ganglioglioma involving the lateral ventricle: A case-based review of a challenging and uncommon presentation.pubmed.ncbi.nlm.nih.gov
  114. Incidental Calcifications of Carotid and Vertebral Arteries: Frequency and Associations in Pediatric Population.pubmed.ncbi.nlm.nih.gov
  115. Radiological Spectrum of Leptomeningeal Medulloblastoma: A Case-Based Literature Review With an Additional Case Report.pubmed.ncbi.nlm.nih.gov

Eğitim amaçlıdır; hasta başında tanı ve tedavi kararının yerine geçmez, tıbbi tavsiye değildir. Metinler yapay zekâ desteğiyle yazıldı ve otomatik bir adımda kaynak alıntılarıyla karşılaştırıldı; bu bir tıbbi doğrulama değildir ve içerik uzman radyolog incelemesinden geçmedi. Klinik kararlarda güncel kılavuzları, kurum protokollerini ve radyoloji raporunu esas alın.