Sinonazal fibroz displazi

Özet

Kraniofasiyal fibroz displazi, normal kemik dokusunun fibro-osseöz matriksle yer değiştirdiği benign bir kemik hastalığıdır ve sinüs çevresindeki kemikleri genişleterek hava boşluklarını daraltabilir. Kontrastsız ince kesit BT, buzlu cam veya karma matriksi, kemik genişlemesini ve sinüs anatomisine etkisini gösterir. Fibroz displazi, radyografik özellikleri diğer fibro-osseöz lezyonlarla örtüşebildiğinden kesin tanı için histopatoloji gerekli olup genişleyici ve destrüktif olmayan seyir gösterir. Optik kanal, orbital duvar veya kafa tabanı komşuluğundaki daralma atlanırsa işlevsel etkilenim ve hastalık yayılımı eksik tarif edilebilir.

Faz ve pencere

Kontrastsız tanısal

Kemik algoritmalı ince kesitlerde genişlemiş kemik içinde buzlu cam, sklerotik ya da karma fibro-osseöz matriks ve sinüs lümeninde biçim değişikliği görülür.

Önerilen pencereler: Kemik (G 1800 / M 400).

BT bulguları

• Maksilla veya başka kraniofasiyal kemik segmentinde düzgün ekspansiyon ve kortikal kabukta korunma ya da incelme.
• Medüller boşluğun homojen buzlu cam görünümünde yoğun matriksle silinmesi.
• Olgunlaşma ve kemik içeriğine bağlı sklerotik veya yamalı karma yoğunluk alanları.
• Lezyon, kaynaklarda belirtildiği üzere genişleyici ve non-destrüktif seyir izler; radyografik özellikler lezyonun boyutuna ve derecesine göre değişkenlik gösterir.
• Maksiller sinüs tabanının veya yan duvarının içe itilmesiyle sinüs hacminde azalma ve asimetri.
• Fibroz displaziye bağlı kemik genişlemesi, etmoid hücrelerin, sfenoid sinüs duvarlarının veya frontal resesin daralmasına ve sinüs ostiumlarının kemiksel deformasyona uğramasına yol açabilir.
• Orbita tabanı, optik kanal veya kafa tabanı açıklıklarında komşuluk nedeniyle oluşan daralma.

Normalde

BT’de lezyonun yerleşimini ve matriksini tanımlayın; uzanımını ve çevre yapılarla ilişkisini değerlendirin.

Ayırıcı tanı

Ossifiye fibrom

keskin sınırlı, çoğu kez kapsüllü ve kemiği dışa doğru iten ekspansil odak oluşturur.

Osteoma

sınırlı, çok yoğun kemik odağı olarak sinüs lümenine projekte olur; kemiğin geniş bir segmentini tutmaz.

Düşük dereceli osteosarkom

korteks yıkımı, düzensiz periostal reaksiyon veya ekstraosseöz yumuşak doku bileşeni varsa benign displaziden uzaklaşılır.

Tuzaklar

• Buzlu cam görünümünü tek başına tanı kabul etmeyin; lezyonun kemiği genişletme biçimi ve sınırının medullaya geçişi ossifiye fibromdan ayrımda önemlidir.
• Sinüs lümenindeki opasifikasyon yalnızca mukozal hastalık olarak yorumlanmamalı; fibroz displazide karakteristik kemik genişlemesi ve duvarların itilmesi ayrıntılı incelenmelidir.
• Belirgin asimetriyi agresif destrüksiyonla eşitlemeyin; düzgün konturlu genişleme fibroz displazide görülebilir, korteks dışına çıkan yumuşak doku kitlesi ise atipiktir.

Kendini dene

1. Genç erişkinin sinüs BT’sinde maksiller kemik düzgün genişlemiş, buzlu cam matriksli ve sinüs tabanı içe itilmiş. En olası tanı nedir?

   • Fibroz displazi
   • Ossifiye fibrom
   • Kronik osteit
   • Maksiller osteom
   Cevabı göster

   Fibroz displazi. Kemiğin segmental ve düzgün genişlemesiyle buzlu cam matriks fibroz displaziyi destekler. Ossifiye fibrom daha keskin sınırlı bir ekspansil odak oluşturur; osteit duvar kalınlaşmasıdır, osteom ise fokal yoğun kemiktir.

2. Buzlu cam matriksli kraniofasiyal kemik lezyonunda sinüs anatomisinin etkisini belirlemek için hangi kıyas en yararlıdır?

   • Karşı maksiller sinüs hacmi
   • Nazal septum kıkırdak kalınlığı
   • Mandibular kondil aralığı
   • Temporal kemik mastoid hücreleri
   Cevabı göster

   Karşı maksiller sinüs hacmi. Karşı maksiller sinüs aynı anatomik düzeyde kontrol sağlar; taban ve duvarların yer değiştirmesi ile lümen daralmasını görünür kılar.

İlgili konular

• Sinonazal ossifiye fibrom
• Kronik sinüs osteiti

Kaynaklar

Bu sayfadaki 30 cümle ve 2 quiz sorusu aşağıdaki kaynaklardan alıntılarla tek tek karşılaştırıldı; 7 cümle bu karşılaştırmada düzeltildi (2026-10-08).

1. Small ethmoid mucocele with intracranial extension associated with fibrous dysplasia: A rare case reportpmc.ncbi.nlm.nih.gov
2. A Huge Intraosseous Hemangioma in the Maxillary Sinus Misdiagnosed as Osteosarcoma: A Case Reportpmc.ncbi.nlm.nih.gov
3. Endoscopic management of uncommon benign maxillary sinus lesions: a case seriespmc.ncbi.nlm.nih.gov
4. Benign Sinonasal Tumors: A 17-Year Single Center Experiencepmc.ncbi.nlm.nih.gov
5. Intracranial aneurysmal bone cysts in association with fibrous dysplasia: Case report and scoping review of case reportspmc.ncbi.nlm.nih.gov
6. Characteristics of sinonasal fibrous dysplasia: experience from a single department.pubmed.ncbi.nlm.nih.gov
7. Ossifying fibromas of the paranasal sinuses: diagnosis and management.pubmed.ncbi.nlm.nih.gov
8. Orbital Involvement In Sinonasal Diseases.pubmed.ncbi.nlm.nih.gov
9. [Application of 3D computer-assisted printing technique combined with plastic titanium mesh in the reconstruction of maxillary defect].pubmed.ncbi.nlm.nih.gov
10. An alternative management approach to paranasal sinus fibro-osseous lesions.pubmed.ncbi.nlm.nih.gov
11. A Clinical and Radiological Approach to the Management of Benign Mesenchymal Sinonasal Tumors.pubmed.ncbi.nlm.nih.gov
12. Sinonasal disease in polyostotic fibrous dysplasia and McCune-Albright Syndrome.pubmed.ncbi.nlm.nih.gov
13. [Surgical management of sinonasal and adjacent skull base benign fibro-osseous lesions].pubmed.ncbi.nlm.nih.gov
14. Role of intraoperative CT-updates during image-guided endoscopic sinus surgery for sinonasal fibro-osseous lesions.pubmed.ncbi.nlm.nih.gov
15. Hyperostotic esthesioneuroblastoma: rare variant and fibrous dysplasia mimicker.pubmed.ncbi.nlm.nih.gov
16. Small ethmoid mucocele with intracranial extension associated with fibrous dysplasia: A rare case report.pubmed.ncbi.nlm.nih.gov
17. Intracranial aneurysmal bone cysts in association with fibrous dysplasia: Case report and scoping review of case reports.pubmed.ncbi.nlm.nih.gov
18. Endoscopic Endonasal Resection of Fibro-Osseous Lesions Involving the Nasal Turbinates: A Report of Two Cases and a Literature Review.pubmed.ncbi.nlm.nih.gov
19. Endoscopic management of uncommon benign maxillary sinus lesions: a case series.pubmed.ncbi.nlm.nih.gov
20. Cavernous venous malformation of the frontal sinus: CT and MRI imaging findings.pubmed.ncbi.nlm.nih.gov
21. Sculpting Solutions: A Case Report of Resection and Reconstruction in an Aggressive Mandibular Juvenile Ossifying Fibroma and Review of Literature.pubmed.ncbi.nlm.nih.gov
22. Benign incidental do-not-touch bone lesions.pubmed.ncbi.nlm.nih.gov
23. Nonproliferative and Proliferative Lesions of the Rat and Mouse Skeletal Tissues (Bones, Joints, and Teeth).pubmed.ncbi.nlm.nih.gov
24. Unusual Manifestations of Sinonasal Osteomas: A Narrative Review.pubmed.ncbi.nlm.nih.gov
25. Polyostotic fibrous dysplasia: Unveiling the complexity of a rare bone disorder through a case report.pubmed.ncbi.nlm.nih.gov
26. Imaging of the skull base and orbital tumors.pubmed.ncbi.nlm.nih.gov
27. When plasmacytoma defies expectations: An unusual maxillary presentation with mixed imaging features in a young patient.pubmed.ncbi.nlm.nih.gov
28. Ossifying fibroma of the maxilla: A case report with literature review.pubmed.ncbi.nlm.nih.gov
29. Imaging of Skull Base Tumors.pubmed.ncbi.nlm.nih.gov
30. Aesthetic and Functional Rehabilitation in Juvenile Ossifying Fibroma: A Case Report.pubmed.ncbi.nlm.nih.gov
31. "Maxillary juvenile ossifying fibroma: A case study of severe tooth displacement and orbital involvement in a pediatric patient".pubmed.ncbi.nlm.nih.gov
32. Cone-beam computed tomography imaging of benign odontogenic lesions in the maxilla: A report of 2 cases.pubmed.ncbi.nlm.nih.gov
33. The GNAS Gene: Fibrous Dysplasia, McCune-Albright Syndrome, and Skeletal Structure and Function.pubmed.ncbi.nlm.nih.gov
34. Malignant Transformation of Musculoskeletal Lesions with Imaging-Pathology Correlation-Part 1: Bone Lesions.pubmed.ncbi.nlm.nih.gov
35. Unveiling Primary Bone Tumors of the Spine: A Review of Essential Imaging Clues.pubmed.ncbi.nlm.nih.gov
36. Musculoskeletal tumors and tumor-like lesions with "dark" signal intensity on T2-weighted MR images: A pictorial review.pubmed.ncbi.nlm.nih.gov
37. Soft Tissue Special Issue: Gnathic Fibro-Osseous Lesions and Osteosarcoma.pubmed.ncbi.nlm.nih.gov
38. EWSR1 -The Most Common Rearranged Gene in Soft Tissue Lesions, Which Also Occurs in Different Bone Lesions: An Updated Review.pubmed.ncbi.nlm.nih.gov
39. Conventional radiography for the assessment of focal bone lesions of the appendicular skeleton: fundamental concepts in the modern imaging era.pubmed.ncbi.nlm.nih.gov
40. International Harmonization of Nomenclature and Diagnostic Criteria (INHAND): Non-proliferative and Proliferative Lesions of the Non-human Primate ( M. fascicularis ).pubmed.ncbi.nlm.nih.gov
41. Nonproliferative and Proliferative Lesions of the Rat and Mouse Endocrine System.pubmed.ncbi.nlm.nih.gov
42. The maxillary sinus: physiology, development and imaging anatomy.pubmed.ncbi.nlm.nih.gov
43. Computed Tomography in Craniofacial Fibrous Dysplasia: A Case Series with Review of Literature and Classification Update.pubmed.ncbi.nlm.nih.gov
44. Masses of developmental and genetic origin affecting the paediatric craniofacial skeleton.pubmed.ncbi.nlm.nih.gov
45. A practical overview of CT and MRI features of developmental, inflammatory, and neoplastic lesions of the sphenoid body and clivus.pubmed.ncbi.nlm.nih.gov
46. Ocular findings in Jansen metaphyseal chondrodysplasia.pubmed.ncbi.nlm.nih.gov
47. 23-year review of spheno-orbital meningioma: clinical, radiological, and pathological insights from 100 cases.pubmed.ncbi.nlm.nih.gov
48. Relationship between maxillary sinus volume and alveolar trabeculation at orthodontic mini-implant sites across vertical skeletal patterns: a cross-sectional CBCT analysis.pubmed.ncbi.nlm.nih.gov
49. Dental Radiographic/Digital Radiography Technology along with Biological Agents in Human Identification.pubmed.ncbi.nlm.nih.gov
50. Neurofibromatosis Type 1 With Cherubism-like Phenotype, Multiple Osteolytic Bone Lesions of Lower Extremities, and Alagille-syndrome: Case Report With Literature Survey.pubmed.ncbi.nlm.nih.gov
51. Imaging-Guided Surgical Decision-Making and Bone Healing in Mandibular Cystic and Tumor-like Lesions: A Case-Based Radiologic Observation.pubmed.ncbi.nlm.nih.gov
52. Jansen metaphyseal chondrodysplasia: analysis of craniofacial manifestations.pubmed.ncbi.nlm.nih.gov
53. Craniovertebral Junction Instability after Oncological Resection: A Narrative Review.pubmed.ncbi.nlm.nih.gov
54. Bone-Preserving Management of Maxillary Cemento-Ossifying Fibroma With Orbital Floor Thinning: A Case Report.pubmed.ncbi.nlm.nih.gov
55. Aggressive Juvenile Trabecular Ossifying Fibroma in a 4-Year-Old: Case Report Bringing Diagnostic Challenges and Surgical Management.pubmed.ncbi.nlm.nih.gov
56. Extensive ossifying fibroma of the mandible: segmental resection and free fibula flap reconstruction.pubmed.ncbi.nlm.nih.gov
57. Review of imaging modalities and radiological findings of calvarial lesions.pubmed.ncbi.nlm.nih.gov
58. Benign and malignant lesions of the mandible and maxilla: imaging findings and systematic approach.pubmed.ncbi.nlm.nih.gov
59. Osteomyelitis of the Jaw Bones and Its Mimics: Resolving the Diagnostic Enigma.pubmed.ncbi.nlm.nih.gov
60. Imaging Features of Mandibular Ramus Osteoma on Computed Tomography: A Case Report With Literature Analysis.pubmed.ncbi.nlm.nih.gov
61. Fibrous dysplasia of the jaws: four cases with conservative and resective surgical management.pubmed.ncbi.nlm.nih.gov
62. Giant Peripheral Osteoma of the Mandibular Antegonial Notch in an Elderly Patient: A Case Report.pubmed.ncbi.nlm.nih.gov
63. Cystic bone Lesions: Diagnostic pitfalls and therapeutic considerations.pubmed.ncbi.nlm.nih.gov
64. Long-term safety and effectiveness of the "OptEase" vena cava filter.pubmed.ncbi.nlm.nih.gov
65. Fibrous Dysplasia Presenting as an Exophytic Gingival Mass: A Rare Clinical Presentation.pubmed.ncbi.nlm.nih.gov
66. Desmoplastic Fibroma of the Mandible in a 10-Year-Old Female Patient: A Case Report.pubmed.ncbi.nlm.nih.gov
67. Prevalence of Incidental Maxillary Sinus Anomalies on CBCT Scans: A Radiographic Study.pubmed.ncbi.nlm.nih.gov
68. Craniofacial Osteomas: From Diagnosis to Therapy.pubmed.ncbi.nlm.nih.gov
69. Bone in Parathyroid Diseases Revisited: Evidence From Epidemiological, Surgical and New Drug Outcomes.pubmed.ncbi.nlm.nih.gov
70. Radiological review of skull lesions.pubmed.ncbi.nlm.nih.gov
71. Imaging approach for jaw and maxillofacial bone tumors with updates from the 2022 World Health Organization classification.pubmed.ncbi.nlm.nih.gov
72. A Review of Posteromedial Lesions of the Chest Wall: What Should a Chest Radiologist Know?pubmed.ncbi.nlm.nih.gov
73. Bone-related disorders of the jaw: A clinico-radiological diagnostic algorithm.pubmed.ncbi.nlm.nih.gov
74. Salvaging Vision: A Study of Non-Traumatic Optic Neuropathies.pubmed.ncbi.nlm.nih.gov
75. Sphenoclival fibrous dysplasia with cyst formation causing abducens nerve palsy in an older patient: illustrative case.pubmed.ncbi.nlm.nih.gov
76. Special Considerations in Pediatric Endoscopic Skull Base Surgery.pubmed.ncbi.nlm.nih.gov
77. Congenital and Breed-Associated Vertebral Anomalies in Dogs and Cats: Developmental Anatomy, Genetic Determinants, and Biological Significance.pubmed.ncbi.nlm.nih.gov
78. Augmented Reality Navigation in Craniomaxillofacial/Head and Neck Surgery.pubmed.ncbi.nlm.nih.gov
79. MRI Investigation of Kidneys, Ureters and Urinary Bladder in Rabbits.pubmed.ncbi.nlm.nih.gov
80. A case of craniofacial polyostotic fibrous dysplasia.pubmed.ncbi.nlm.nih.gov
81. A review of the oral health of individuals with disabilities in Puerto Rico and among U.S. Hispanics.pubmed.ncbi.nlm.nih.gov
82. A Huge Intraosseous Hemangioma in the Maxillary Sinus Misdiagnosed as Osteosarcoma: A Case Report.pubmed.ncbi.nlm.nih.gov
83. Histological Diversity, Diagnostic Challenges, and Surgical Treatment Strategies of Fibrous Dysplasia of Upper and Mid-Thirds of the Craniomaxillofacial Complex.pubmed.ncbi.nlm.nih.gov
84. Clival and Paraclival Lesions: A Pictorial Review.pubmed.ncbi.nlm.nih.gov
85. Rare Diseases of the Middle Ear and Lateral Skull Base.pubmed.ncbi.nlm.nih.gov
86. Giant Oncocytic Sinonasal Papilloma: A Rare Case.pubmed.ncbi.nlm.nih.gov
87. Adjacent Maxillary Bone Microarchitecture in Patients with Asymmetric Bilateral Lund-Mackay Scores: A Pilot Retrospective Within-Subject Analysis Using CBCT.pubmed.ncbi.nlm.nih.gov
88. Uremic leontiasis ossea: distinctive imaging features allow differentiation from other clinical causes of leontiasis ossea.pubmed.ncbi.nlm.nih.gov
89. Efficiency and Safety of Dental Implantation in the Area of Hyperdense Jaw Lesions: A Narrative Review.pubmed.ncbi.nlm.nih.gov
90. Surgical Management of a Case of Frontoparietal Fibrous Dysplasia.pubmed.ncbi.nlm.nih.gov
91. Surgically Treated Benign Bone Tumors and Tumor-like Conditions in the Pediatric Population-A 10-Year Institutional Experience.pubmed.ncbi.nlm.nih.gov
92. Craniofacial Fibrous Dysplasia to Affect or Not the Optic Nerve in Long-Term Follow-Up of Three Cases.pubmed.ncbi.nlm.nih.gov
93. Bone Regeneration After Maxillary Sinus Augmentation with Allogeneic and Xenogeneic Biomaterials with Adjunctive Photobiomodulation: Histological and Radiological Secondary Outcomes of a Randomized Clinical Trial.pubmed.ncbi.nlm.nih.gov
94. From Structure to Aesthetics: The Importance of Nasal Bone Thickness in Rhinoplasty Planning.pubmed.ncbi.nlm.nih.gov
95. Craniofacial Ossifying Fibromas in Children: Clinical Variability and Surgical Outcomes in a Case Series.pubmed.ncbi.nlm.nih.gov
96. Emerging and re-emerging infectious disease in otorhinolaryngology.pubmed.ncbi.nlm.nih.gov
97. Endoscopic endonasal transsphenoidal surgery for unusual sellar lesions: eight cases and review of the literature.pubmed.ncbi.nlm.nih.gov
98. A Rare and Atypical Manifestation of Intraosseous Hemangioma in the Zygomatic Bone.pubmed.ncbi.nlm.nih.gov
99. Biomechanical Effects of Horizontal, Vertical, and Combined Misfits in Full-Arch Implant-Supported Titanium Frameworks: A Three-Dimensional Finite Element Analysis.pubmed.ncbi.nlm.nih.gov
100. Rare Diseases of the Orbit.pubmed.ncbi.nlm.nih.gov
101. Comprehensive review on endonasal endoscopic sinus surgery.pubmed.ncbi.nlm.nih.gov
102. Osseous Hemangioma of the Inferior Turbinate: A Case Report and Review of Literature.pubmed.ncbi.nlm.nih.gov
103. Ectopic ACTH-Secreting Pituitary Adenoma of the Maxillary Sinus: A Rare Cause of Cushing's Syndrome.pubmed.ncbi.nlm.nih.gov
104. Ossifying Fibroma of the Frontal Sinus: A Case Report and Literature Review.pubmed.ncbi.nlm.nih.gov
105. Craniofacial fibrous dysplasia: Molecular insights, long-term institutional experience, and evolving surgical strategies.pubmed.ncbi.nlm.nih.gov
106. Modern technology complements classic technique: 3D-printed inter-locking cutting guides for frontal sinus osteoma resection and reconstruction with split-calvarial bone graft.pubmed.ncbi.nlm.nih.gov
107. Cone-Beam Computed Tomography Imaging of Primary Non-Hodgkin Lymphoma of the Jaws: A 6-Case Series.pubmed.ncbi.nlm.nih.gov
108. Radiographic Assessment of Normal Periapical Bone Density: A Descriptive Analysis Based on Digital Imaging.pubmed.ncbi.nlm.nih.gov
109. Non-Ossifying Fibromas: A 2025 Review.pubmed.ncbi.nlm.nih.gov
110. Radiolucent Lesions of the Jaws: An Attempted Demonstration of the Use of Co-Word Analysis to List Main Similar Pathologies.pubmed.ncbi.nlm.nih.gov
111. CT Anatomy of the Skull in Lamb and Adult Romane Sheep.pubmed.ncbi.nlm.nih.gov
112. Cadaveric Study of the Juvenile Grey Heron's (Ardea cinerea) Nasal Cavity and Associated Structures Through Computed Tomography and Anatomical Sections.pubmed.ncbi.nlm.nih.gov
113. Ectopic maxillary third molar associated with an odontogenic keratocyst in the maxillary Sinus presenting as refractory unilateral sinonasal symptoms: a case report with implications for early dental diagnosis.pubmed.ncbi.nlm.nih.gov
114. How Clinical and Radiological Findings in Chronic Mandibular Osteomyelitis Do Not Always Correlate: Diagnostic Dilemmas in Dental-Related Bone Inflammations.pubmed.ncbi.nlm.nih.gov
115. Pediatric Desmoplastic Fibroma of the Jaws: A Comprehensive Review of Clinical Presentation, Management, and Outcomes.pubmed.ncbi.nlm.nih.gov

Eğitim amaçlıdır; hasta başında tanı ve tedavi kararının yerine geçmez. İçerik yapay zekâ destekli bir süreçle güncel literatüre göre cümle cümle kaynaklarla karşılaştırıldı, ancak uzman radyolog incelemesinden geçmedi. Klinik kararlarda güncel kılavuzları, kurum protokollerini ve radyoloji raporunu esas alın.